I am a big fan of 45acp, especially in revolvers using moonclips. The clips make reloads much easier (and faster) than speedloaders. This S&W 625-2 makes a great primary home defense gun, backed up by a Sig P220. The manual of arms for a revolver is much simpler than any semi-auto pistol, especially for less experienced shooters. As far as the 357 vs. 38 special debate goes, I prefer 38 +P for controllability in a medium or large frame revolver,.
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