I've used 180gr Nosler Partitions with good sucess in my -06. I put down a 600lb elk cow in Oct with that bullet over 56.3gr of IMR 4350, Winchester LR primers and Winchester brass. She was 40 yds away and took 2 steps before she fell over. Thru and thru wound channel with about a quarter size exit wound.
During the load development, I got 3/4" groups @ 100 yards and the 5 shot string averaged 2850fps out of my 21" Savage 110 series rifle.