You can. Just a question of what you are going for. A good single stage is probably going to be more accurate than a really good progressive. I guess just a question if the fraction of a thousandth of an inch matters to you. If you are measuring and trickling each powder drop, I don't think I'd want to do that on a progressive. Not that you can't, I just think the design of them doesn't lend itself to easily charging a cartridge anyway other than an automated powder drop. A single stage with a lee powder through expander or powder through charging die is the best way, IMHO. A lee classic with those dies also worked pretty well. Or the way I do it is I use the auto drum, pull the case out, measure, trickle if needed, back on the press. That's maybe a hair easier than a progressive. Probably not easier enough to really matter there though. Just more to reach through or around on a progressive depending on what station you are reaching for.For those that like to load on single stage for some things but use a progressive for others, why not use a progressive and load one at a time as if it were a single stage? I’ve taught people how to use a progressive by going through each stage separately, explaining things as I went along. As Tickg pointed out above, the progressive can be used as a single stage, and still produce rounds faster than on a single stage Because the dies don’t have to be changed after each step.